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KMID : 0363220150530090677
Korean Journal of Dermatology
2015 Volume.53 No. 9 p.677 ~ p.683
The Effectiveness of Light Emitting Diodes with 592 nm Yellow Light for Korean Photoaged Skin
Moon Ki-Rang

Kwon Hyuck-Hoon
Suh Dae-Hun
Yun Sook-Jung
Lee Seung-Chul
Lee Jee-Bum
Abstract
Background: As aging occurs, the skin develops more wrinkles and pigmentation, becomes drier, and loses its elasticity. In previous reports, light-emitting diode (LED) phototherapy was proven to stimulate collagen synthesis and accelerate fibroblast-myofibroblast transformation, which has a composite rejuvenation effect.

Objective: To evaluate the effectiveness and safety of LED phototherapy with 592 nm yellow light for photoaged skin.
Methods: Forty patients with photoaged skin (Korean photographic scale; grade 4¡­7) were enrolled and treated with an LED device producing 592¡¾10 nm yellow light for 5 minutes twice a week for 4 weeks. The skin changes were assessed at 0, 2, 4, and 8 weeks by clinical photographs and the Cutometer¢ç & Mexameter¢ç (MPA 580, Courage£«Khazaka Electronic GmbH, Koln, Germany). Measurements were made on the cheek, periorbital area, nasolabial fold, and glabella.
Results: At the final visit at 8 weeks, the Cutometer¢ç parameters R4 and R6 decreased significantly compared to before treatment, from 0.118 to 0.099 for the periorbital (p=0.017) and 0.517 to 0.425 for the nasolabial fold (p=0.003). The average melanin index decreased significantly, from 133.65 to 124.55 (p£¼0.005). Fine improvement of wrinkles was shown grossly by reviewing follow-up clinical photographs. No adverse reactions occurred. LED phototherapy with 592¡¾10 nm wavelength can be effective and safe in the treatment of photoaged skin.

Conclusion: The findings suggest the LED with 592 nm yellow light might be an adjuvant therapeutic tool for photoaged skin.
KEYWORD
Photoaged skin, 592 nm light emitting diode, LED, Phototherapy
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